Puriri Knoll Rhodesian Ridgebacks

Knowledge fuels success, 30 yrs of Breeding, Exhibiting and learning sees us produce carefully considered & consistently "Fit for Purpose" hounds

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Health Testing

EOAD

Early Onset Adult Deafness

 

Genetic testing of the EPS8L2 gene in the Rhodesian Ridgeback will reliably determine whether a dog is a genetic Carrier of EOAD.

EOAD is inherited in an Autosomal Recessive manner in dogs, meaning that they must receive two copies of the mutated gene (one from each parent) to develop the disease.

In general, carrier dogs do not have features of the disease but when bred with another carrier of the same mutation, there is a risk of having affected pups.

Each pup that is born to this pairing has a 25% chance of inherit ing the disease and a 50% chance of inheriting one copy and being a carrier of the EPS8L2 gene mutation.

Reliable genetic testing is important for determining breeding practices.  Because symptoms may not appear until adulthood, genetic testing should be performed before breeding.

In order to eliminate this mutation from breeding lines and to avoid the potential of producing affected pups, breeding of known carriers to each other is not recommended.  Rhodesian Ridgebacks that are not carriers of the mutation have no increased risk of having affected pups.